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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1df530254f2a29d49366c495f48525ed22b33ff43c88e23d10bed04b54c57107' 
  AND token = 'uf5gPdfs7t7oLWhxUgSdNRop1dEoBevZvkpb37BNjAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}