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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b5cec3368b4f99ca16f15e706c2708332b8b69e35008e6575020536fb54e2f' 
  AND token = 'Wsul/g5wMTLOnTYMSIPz9rFuvPrYzXnIO+JN9iQ4WxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}