SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '554677c08f78f37e4dafbce7892beea1a0967c86f8b065f9d2f410881f68c29a' 
  AND token = 't/i8kzcAGV1Lbs6bgg71ZPoRIQRvUktE+hcB33cwhCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}