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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2d7606c4f11cea3b661bc5d23915360a8abc7bd563433ce665e046e42743d04' 
  AND token = '/gSu5G9D6XuEv7/3Cpv5X3QOHV+g1SoSmqzTN3TWiDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}