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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e17a708572e29ff2e8fc0b324d378db98c048e8816a39e9bb6fd6ae21a6d5b1' 
  AND token = 'TalGn4KswWEzQkI/uDCGZcpxEJ0o3LqVzT08pg6zy9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}