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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66b77b9cee31074e86dfa9fd269f13ef2983055961764f5754f967ed4b138a86' 
  AND token = 'E6zYGZtSbBDbKdRiWd+tY791fkhGvzk35KypdwuAxHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}