SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5967ceeee2d2a2799b0c38f61f1a4b16faebd6507edec6766923a617cde0d831' 
  AND token = '44ivIUecKm2FEgPJqvXiz37gxGeI1cnbbsQZ13nOF1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}