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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22334eafbf8ef3adf3a5acb0fe74dbf17929c7a656d841b6f3d2e8a57979447' 
  AND token = 'LA01IUVA2EW6SabIGnJ+j+SvHd3iGvbvb2FKvvU8l/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}