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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6517641ae0fbaa0b96bf250ababe2ad7a0d9dc32fe4254c57dc6f4f22af3c3b' 
  AND token = 'LYaD/NF8+o6zYJJNZ450AA1/NKvDGLumJ7AF7vjHe3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}