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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64e518016b093a75178e36c2c15d0304b105fc0df5a34aa2cea8c74a148f0cf4' 
  AND token = 'Eki5xgLSpLevOlzZy4VdgiMXF3L9cGxAY2GkYTpBaB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}