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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef8b1d60f7b4abfdad7648160494fff16a69fbefb07b446b0b00835e68fb3a8d' 
  AND token = 'X+5Uuf2/m+kTiSh9f0IzcBywqy7vkf19BPDQaRnIJz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}