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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33383a4e0602605e110458b7dbc13d1eb3d58d539917dfff4451f99b698aeb71' 
  AND token = 'DgozBT/p7WVNoFADBGO/FCP5eeUHrVlAv/zsV0j8VR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}