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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3880c3342b8227401507938e92f46cfeba7c99c09a59d4ec8b4ab3afc84ecd6' 
  AND token = 'FvLd12+hr3JOmDxiOZGP/M2n1YiY9nneSVRGLW58zkc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}