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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f6c9cd9870155c4a13e5dc8eded791e15a82c3c4fc774752f28479b60c30f62' 
  AND token = 'Na1iWeLWQ+qR/OWXC7dZD1JV6XRY2Sv86IB2/eUxtVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}