SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b54416cab5ce2b7a121302754589cfd3092f95da2d53130198d70e9cfb97fa9d' 
  AND token = 'QMFjoDwcl5NPzuAbSl6807rcVC5xGGBZ3R8Xn80VuC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}