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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43b69fda9cd990a124fdc844893ba5f715432b7f4fedc0c4e3c647756f1ce32' 
  AND token = 'R6aa9sRlrZgtqq+Vj5gN93MaG3dUO/taRU5ogM/NXnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}