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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c00011c51d2bca113ff63f492cd1cbb615a1f10373a889f89082fd5fcdc7892' 
  AND token = '/B5ipXIcqSy4i4Ttlq1vivPKISBfqXaKlayVwKfaBjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}