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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '106347fc14da475835cfab4287d801583de3378baee70ecce3e85734fe4c604a' 
  AND token = '05LJQ2F5rEPMBE6U+wyuEA2WT5lCBlu6MFxTHqWJ5ZM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}