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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f0ba58e8721fee4de8833d94078d1b0bd19d5bc1e7d3c0e507e5dd15c64d394' 
  AND token = 'HeqV0S+F5NhVFWJfcqt7XGbEl3qxZrRSg3EeJEmGfBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}