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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5be71e65386d669d5c042983466c8ec87414db4aca19df442ad26d3e6c5cf456' 
  AND token = 'zQ9Jnyx8pBVhD2OeRyniGovXKABoG9AmVhlJ7JvUsRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}