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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fb3010c18a38d6149899a5d69655699574124fb60cb8a78ab1341669982249f' 
  AND token = 'v2A/UzEcfPuPB2ozrHwE/DqmoiE1Nzxp4iGRrRsXnyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}