SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20f2d836b54b15b9099b51f09f0aec268c6bbbf06e12d4fa334c549f52cd6a9a' 
  AND token = 'MNulrOQ2aLZYRsdXlA7gMWHhbLx5+YE4ZeGSanxP3jk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}