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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea4614cfbd407494be438ccbe0e7b1d52dfc368945037b0f800861d3a62f2632' 
  AND token = 'HPCp31hB6vupk851fytMlaS99FF8AL1mYVW8+ylIiow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}