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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a81ee793b613bcba61407b97a946f46ce2f9a82e3c0a8f2edc29ad689f7676e' 
  AND token = 'jCc+TDAU+EtuqmiBLFQcz35bFQ1bSuYm3bsHz6sGlzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}