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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8758ce51cf2b0542741de25fc9f0cf30fdf6cf91361c73b6c64bd2016c2cd042' 
  AND token = 'dyLOMOxCuIF9fDqfsA/Z/DhxnEqXHzFSeN3LsChD8Po=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}