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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '001808ec6ecdb4d68e03d6713dc120b495a162afa5999384eca4f11490538012' 
  AND token = 'pu4116Lzen8d03HXivTm99dzeohV//d7jtF8GGby1IQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}