SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ba7b3a5a0dc17a106f03e04f8d01d1bab160147f1e447b671ce19b02660e4db' 
  AND token = 'xl/vuKkZ0cx0klYjxzflDO73YXT8Qj8MmXBzcV2HCwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}