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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '972072b4b728900215eb0a457e629de9e1769eed4c29be2a969c412f36c75bea' 
  AND token = 'U4JgaYllQvrpYOjEoS22HqSEWhb+wGQWMOkQgUJAtAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}