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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ec49f55a9bb2d957a3ad2facd16933e309b579feeb190e5dfb4ab70722e4ffb' 
  AND token = 'GnhDcHszyUnWTH7xeVseS1Wx2gcLJ32LtVp1J3IpTWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}