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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a69015dbc96eb08bfa5ef0d47e3d140954e7c65d7c393ba988b39977ff1bdadf' 
  AND token = 'efMmTQBBlB3UDQw76mnQcs1VTB3MCbNTAwT2GzM4h+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}