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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '743bdd81ad1771f89b97f5952bbd0ca92439331576b3921020b848537e6ba89d' 
  AND token = 'KG6nwb4ZYoNdLueE0ORUM/3EAWaWSc8CqQIp0qbVKAw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}