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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42f31455f81aaeca324179fd77783a755e25153d6ff75a7da22b56975b3fb0f' 
  AND token = 'F6QEJNKM/H9nj4pKpU1nxnXdvger4n0zmBRRH2xMeMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}