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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '719b8d43f306deed2a4cce26a86a1c82468fb9fa3999b7c2483896f0b11a4a9c' 
  AND token = 'VKXRD8UEHVWVo1E+YirL6z30zBqUHastWQh9+XIDLBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}