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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '846ecf2c158d7e3ed93119f3458c3e8e611d83e1364a3d758a2fd9aa7b2dd048' 
  AND token = '5P71nwYemY/x6rlXKCHqhyCFY+ZxlCInnPq3vX/owiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}