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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5658c689ee78e69ba75fdbf3a87640ca66b307653695668b8534d4925ed79bb9' 
  AND token = 'e/IAENmFzBA7QzNceUDuFaGggLqG1G2s4C7EGspcVYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}