SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd349c1c5015124e9a86ea1aab6875dcbb2328d037d5b7013fd3ea4a81d641299' 
  AND token = 'PC+nWh+jTk8xjE7QFEEbFXG/lL0MCK2MXX/Yug/kDSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}