SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc6daeaa6f683acd37f89bbb86a5a42e4f4d11b311445b7bdc00521b2f9dec04' 
  AND token = 'xe3RhUSwdfN+DNzk/owEqdGVORaaohrpDYEkUbUDFlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}