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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dc6baa8aaa6975cfce8b40725af25d427975d5806a34123f4aef8841f1b1649' 
  AND token = 'KEt/JzrNFQQ0PQqtCp5X/x4KFvKXodUulIxdhd8DAxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}