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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9e43ba33083e436cd5d17ab82b1f9344bde586481a66edd1e5e81f942e81360' 
  AND token = 'cfWNaUPVHgd4I1qUGyWJ5mJF0/814FgzxTOa/3djvjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}