SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fd7a274ddb146e96545deac98b969af4331e7d07a90f6198ccb1640bb53b776' 
  AND token = '+SV44lZyQ8e6X6FLeDnKJanC/KnSB65B/cSHNIcUtdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}