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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4876fe0ec924cb497d4cd5a73df557eeac54ae0998329c45078974b7cae45083' 
  AND token = 'UTv8kT+zGpaoT2aaiOzwXB+tFUXOuj9zkCR4cs2kE48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}