SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea8530d854b1fa126e6f32aaa7a19889ef49dfb4b16aa664b891e6dbee5a2357' 
  AND token = '8G4x88PiRV+4U/Uc2j6M5f4FRtg0mLlwyoIFqp24wOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}