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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de835cfd4683e15f23bc7e4f31dd855e47077000547c0aeec0dbafa7a7ba209e' 
  AND token = 'FxJ1k0JZn+ur6RCkIX6EpsVrLeR7GshmuL1KcDk/oM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}