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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7de8d7477f2bcc022a5a964faa735a64faca93275f99b9a31bbb1ffa4251402f' 
  AND token = 'HTKYOcdeE3u/OOBxUrHM81iSQ0IgjpKR0sYv/JimXkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}