SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af0d742b3ea6ffcbc2a89271639b93f46affe5f288652a3a611fdc55cd92eb70' 
  AND token = 'Bh6QlMBSOWwfgIatC/2+syfiC7jADFHA3Pihsn0H3fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}