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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a4f93df2a87ad2673eada268f9b4c8b9d3c3b72ccf228d31b2cde6f35f45d14' 
  AND token = 'PhnNnhSPT+bXWvTM0HuQO/xlj4DCo68vUBsfs56nf38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}