SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81a18669645e3949228ff6dca873e14178636a086e092ecf3cc33acc5464d357' 
  AND token = 'zAcDBn37CyGcNS3SP1tKOmn1+IXMd/BX+AIbFe01m3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}