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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcb1c057a9cfe1123bfc52f56257893f80095b3c693591181a0058a838e8ba47' 
  AND token = 'dnXePeNuHECRpmxx065cBGMbtrCKVaRXbMhUGpDP5uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}