SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44cd67eb0010e0493348f1e7e603c6feea2606d0c0280e22a2711703f8d01a77' 
  AND token = 'DQM6JU2zMdWHm6O9Qro+JocYUgdYYG9fr4A96SuMAjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00156

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}