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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5109f2a13cdf697b87c0c85a1289c662905f9ef4361e03f651be641b2d15e417' 
  AND token = 'o4dMT44Ch2xmq95T7Wskeo0+ZXvyNA5xyiZtazJT6Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}